Lipid metabolic reprogramming in cancer cells.
Ontology highlight
ABSTRACT:
SUBMITTER: Beloribi-Djefaflia S
PROVIDER: S-EPMC4728678 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Publications
Lipid metabolic reprogramming in cancer cells.
Beloribi-Djefaflia S S Vasseur S S Guillaumond F F
Oncogenesis 20160125
Many human diseases, including metabolic, immune and central nervous system disorders, as well as cancer, are the consequence of an alteration in lipid metabolic enzymes and their pathways. This illustrates the fundamental role played by lipids in maintaining membrane homeostasis and normal function in healthy cells. We reviewed the major lipid dysfunctions occurring during tumor development, as determined using systems biology approaches. In it, we provide detailed insight into the essential ro ...[more]
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