Ontology highlight
ABSTRACT:
SUBMITTER: Blachowska E
PROVIDER: S-EPMC4729164 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Blachowska Ewa E Petriczko Elżbieta E Horodnicka-Józwa Anita A Skórka Agata A Pelc Magdalena M Krajewska-Walasek Małgorzata M Walczak Mieczysław M
Italian journal of pediatrics 20160126
<h4>Background</h4>Costello syndrome is a rare syndrome of multiple congenital anomalies. The typical clinical traits include dysmorphic craniofacial features, skin hyperpigmentation and excess, feeding difficulties leading to severe postnatal growth retardation, short stature, joint hypermobility, and delayed psychomotor development. Additionally, Costello syndrome may present with an increased incidence of congenital heart disease, hypertrophic cardiomyopathy, and increased risk of both benign ...[more]