Ontology highlight
ABSTRACT:
SUBMITTER: Portnoy E
PROVIDER: S-EPMC4729766 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Portnoy Emma E Vakruk Natalia N Bishara Ameer A Shmuel Miriam M Magdassi Shlomo S Golenser Jacob J Eyal Sara S
Theranostics 20160101 2
Cerebral malaria (CM) is a major cause of death of Plasmodium falciparum infection. Misdiagnosis of CM often leads to treatment delay and mortality. Conventional brain imaging technologies are rarely applicable in endemic areas. Here we address the unmet need for a simple, non-invasive imaging methodology for early diagnosis of CM. This study presents the diagnostic and therapeutic monitoring using liposomes containing the FDA-approved fluorescent dye indocyanine green (ICG) in a CM murine model ...[more]