Ontology highlight
ABSTRACT:
SUBMITTER: Elajaili H
PROVIDER: S-EPMC4731354 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Elajaili Hanan H Biller Joshua R JR Rosen Gerald M GM Kao Joseph P Y JP Tseytlin Mark M Buchanan Laura A LA Rinard George A GA Quine Richard W RW McPeak Joseph J Shi Yilin Y Eaton Sandra S SS Eaton Gareth R GR
Journal of magnetic resonance (San Diego, Calif. : 1997) 20150912
Measurement of thiol-disulfide redox status is crucial for characterization of tumor physiology. The electron paramagnetic resonance (EPR) spectra of disulfide-linked dinitroxides are readily distinguished from those of the corresponding monoradicals that are formed by cleavage of the disulfide linkage by free thiols. EPR spectra can thus be used to monitor the rate of cleavage and the thiol redox status. EPR spectra of (1)H,(14)N- and (2)H,(15)N-disulfide dinitroxides and the corresponding mono ...[more]