Exploring the physiological correlates of chronic mild traumatic brain injury symptoms.
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ABSTRACT:
SUBMITTER: Astafiev SV
PROVIDER: S-EPMC4732189 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Publications
Exploring the physiological correlates of chronic mild traumatic brain injury symptoms.
Astafiev Serguei V SV Zinn Kristina L KL Shulman Gordon L GL Corbetta Maurizio M
NeuroImage. Clinical 20160106
We report on the results of a multimodal imaging study involving behavioral assessments, evoked and resting-state BOLD fMRI, and DTI in chronic mTBI subjects. We found that larger task-evoked BOLD activity in the MT+/LO region in extra-striate visual cortex correlated with mTBI and PTSD symptoms, especially light sensitivity. Moreover, higher FA values near the left optic radiation (OR) were associated with both light sensitivity and higher BOLD activity in the MT+/LO region. The MT+/LO region w ...[more]
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