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Alpha and Beta Type 1 Interferon Signaling: Passage for Diverse Biologic Outcomes.

ABSTRACT: Type I interferon (IFN-I) elicits a complex cascade of events in response to microbial infection. Here, we review recent developments illuminating the large number of IFN-I species and describing their unique biologic functions.

SUBMITTER: Ng CT 

PROVIDER: S-EPMC4733246 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature

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Alpha and Beta Type 1 Interferon Signaling: Passage for Diverse Biologic Outcomes.

Ng Cherie T CT   Mendoza Juan L JL   Garcia K Christopher KC   Oldstone Michael B A MB  

Cell 20160101 3

Type I interferon (IFN-I) elicits a complex cascade of events in response to microbial infection. Here, we review recent developments illuminating the large number of IFN-I species and describing their unique biologic functions. ...[more]

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