Ontology highlight
ABSTRACT:
SUBMITTER: Fuccillo MV
PROVIDER: S-EPMC4733560 | biostudies-literature | 2015 Jul
REPOSITORIES: biostudies-literature
Fuccillo Marc V MV Földy Csaba C Gökce Özgün Ö Rothwell Patrick E PE Sun Gordon L GL Malenka Robert C RC Südhof Thomas C TC
Neuron 20150701 2
Neurexins are considered central organizers of synapse architecture that are implicated in neuropsychiatric disorders. Expression of neurexins in hundreds of alternatively spliced isoforms suggested that individual neurons might exhibit a cell-type-specific neurexin expression pattern (a neurexin code). To test this hypothesis, we quantified the single-cell levels of neurexin isoforms and other trans-synaptic cell-adhesion molecules by microfluidics-based RT-PCR. We show that the neurexin repert ...[more]