HIV infection and arterial stiffness among older-adults taking antiretroviral therapy in rural Uganda.
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ABSTRACT:
SUBMITTER: Siedner MJ
PROVIDER: S-EPMC4733585 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
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HIV infection and arterial stiffness among older-adults taking antiretroviral therapy in rural Uganda.
Siedner Mark J MJ Kim June-Ho JH Nakku Ruth Sentongo RS Hemphill Linda L Triant Virginia A VA Haberer Jessica E JE Martin Jeffrey N JN Boum Yap Y Kwon Douglas S DS Tsai Alexander C AC Hunt Peter W PW Okello Samson S Bangsberg David R DR
AIDS (London, England) 20160201 4
HIV infection is associated with arterial stiffness, but no studies have assessed this relationship in sub-Saharan Africa. We enrolled 205 participants over 40 years old in Uganda: 105 on antiretroviral therapy for a median of 7 years, and a random sample of 100 age and sex-matched HIV-uninfected controls from the clinic catchment area. The prevalence of arterial stiffness (ankle brachial index > 1.2) was 33%, 18%, 19% and 2% in HIV+ men, HIV- men, HIV+ women, and HIV- women. In multivariable m ...[more]
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