Ontology highlight
ABSTRACT:
SUBMITTER: Samniang B
PROVIDER: S-EPMC4735283 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Samniang Bencharunan B Shinlapawittayatorn Krekwit K Chunchai Titikorn T Pongkan Wanpitak W Kumfu Sirinart S Chattipakorn Siriporn C SC KenKnight Bruce H BH Chattipakorn Nipon N
Scientific reports 20160201
Long-term high-fat diet (HFD) consumption leads to not only obese-insulin resistance, but also impaired left ventricular (LV) function. Vagus nerve stimulation (VNS) has been shown to exert cardioprotection. However, its effects on the heart and metabolic parameters under obese-insulin resistant condition is not known. We determined the effects of VNS on metabolic parameters, heart rate variability (HRV) and LV function in obese-insulin resistant rats. Male Wistar rats were fed with HFD for 12 w ...[more]