Ontology highlight
ABSTRACT:
SUBMITTER: Nolivos S
PROVIDER: S-EPMC4738335 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Nolivos Sophie S Upton Amy L AL Badrinarayanan Anjana A Müller Julius J Zawadzka Katarzyna K Wiktor Jakub J Gill Amber A Arciszewska Lidia L Nicolas Emilien E Sherratt David D
Nature communications 20160128
The Escherichia coli SMC complex, MukBEF, forms clusters of molecules that interact with the decatenase topisomerase IV and which are normally associated with the chromosome replication origin region (ori). Here we demonstrate an additional ATP-hydrolysis-dependent association of MukBEF with the replication termination region (ter). Consistent with this, MukBEF interacts with MatP, which binds matS sites in ter. MatP displaces wild-type MukBEF complexes from ter, thereby facilitating their assoc ...[more]