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A preliminary method development study to identify potential stroke biomarkers in plasma using multiple chromatographies with nanoLC-ESIMS detection.


ABSTRACT: Stroke is the leading cause of disability in the USA. Rapid, reliable diagnosis via a point-of-care blood test may facilitate earlier treatment to reduce disability. We have recently reported detailed methods of chromatographic separations of plasma samples coupled with nanoESI-ion trap a list of proteins which are viable candidates for further investigation as stroke biomarkers.

SUBMITTER: Kodali P 

PROVIDER: S-EPMC4739646 | biostudies-literature | 2013 Oct

REPOSITORIES: biostudies-literature

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A preliminary method development study to identify potential stroke biomarkers in plasma using multiple chromatographies with nanoLC-ESIMS detection.

Kodali Phanichand P   Landero-Figueroa Julio A JA   Caruso Joseph J   Adeoye Opeolu O  

Journal of neural transmission (Vienna, Austria : 1996) 20130413 10


Stroke is the leading cause of disability in the USA. Rapid, reliable diagnosis via a point-of-care blood test may facilitate earlier treatment to reduce disability. We have recently reported detailed methods of chromatographic separations of plasma samples coupled with nanoESI-ion trap a list of proteins which are viable candidates for further investigation as stroke biomarkers. ...[more]

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