Ontology highlight
ABSTRACT:
SUBMITTER: Gu H
PROVIDER: S-EPMC4739682 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Gu Hongbo H Ren Jian Min JM Jia Xiaoying X Levy Tyler T Rikova Klarisa K Yang Vicky V Lee Kimberly A KA Stokes Matthew P MP Silva Jeffrey C JC
Molecular & cellular proteomics : MCP 20151203 2
A robust method was developed and optimized for enrichment and quantitative analysis of posttranslational modifications (PTMs) in serum/plasma samples by combining immunoaffinity purification and LC-MS/MS without depletion of abundant proteins. The method was used to survey serum samples of patients with acute myeloid leukemia (AML), breast cancer (BC), and nonsmall cell lung cancer (NSCLC). Peptides were identified from serum samples containing phosphorylation, acetylation, lysine methylation, ...[more]