Ontology highlight
ABSTRACT:
SUBMITTER: Kim HL
PROVIDER: S-EPMC4740313 | biostudies-literature | 2015 Nov
REPOSITORIES: biostudies-literature
Kim Hyung L HL Halabi Susan S Li Ping P Mayhew Greg G Simko Jeff J Nixon Andrew B AB Small Eric J EJ Rini Brian B Morris Michael J MJ Taplin Mary-Ellen ME George Daniel D
EBioMedicine 20150908 11
<h4>Background</h4>Prognosis associated with metastatic renal cell carcinoma (mRCC) can vary widely.<h4>Methods</h4>This study used pretreatment nephrectomy specimens from a randomized phase III trial. Expression levels of candidate genes were determined from archival tumors using the OpenArray® platform for TaqMan® RT-qPCR. The dataset was randomly divided at 2:1 ratio into training (n = 221) and testing (n = 103) sets to develop a multigene prognostic signature.<h4>Findings</h4>Gene expression ...[more]