Ontology highlight
ABSTRACT:
SUBMITTER: Liu N
PROVIDER: S-EPMC4741479 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Liu Ning N Boohaker Rebecca J RJ Jiang Chunling C Boohaker James R JR Xu Bo B
Oncotarget 20151001 33
MicroRNA, a class of small non-coding RNAs, play critical roles in the cellular response to DNA damage induced by ionizing irradiation (IR). Growing evidence shows alteration of miRNAs, in response to radiation, controls cellular radiosensitivity in DNA damage response pathways. However, it is less clear about the clinical relevance of miRNA regulation in radiosensitivity. Using an in vitro system, we conducted microarray to identify a miRNA signature to assess radiosensitivity. The data were va ...[more]