Ontology highlight
ABSTRACT:
SUBMITTER: Hong Y
PROVIDER: S-EPMC4741601 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Hong Yingcai Y Chen Wen W Du Xiaojun X Ning Huiwen H Chen Huaisheng H Shi Ruiqing R Lin Shaolin S Xu Rongyu R Zhu Jinrong J Wu Shu S Zhou Haiyu H
Oncotarget 20151001 31
Sex-determining region Y-box 9 (SOX9), a vital transcription factor, play important roles in numerous biological and pathological processes. However, the clinical significance and biological role of SOX9 expression has not been characterized in human esophageal squamous cell cancer (ESCC). Herein, we found that SOX9 was markedly upregulated, at both mRNA and protein level, in ESCC cell lines and ESCC tissues and that SOX9 expression was significantly correlated with tumor clinical stage, T class ...[more]