CRC-113 gene expression signature for predicting prognosis in patients with colorectal cancer.
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ABSTRACT:
SUBMITTER: Nguyen MN
PROVIDER: S-EPMC4741632 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Publications
CRC-113 gene expression signature for predicting prognosis in patients with colorectal cancer.
Nguyen Minh Nam MN Choi Tae Gyu TG Nguyen Dinh Truong DT Kim Jin-Hwan JH Jo Yong Hwa YH Shahid Muhammad M Akter Salima S Aryal Saurav Nath SN Yoo Ji Youn JY Ahn Yong-Joo YJ Cho Kyoung Min KM Lee Ju-Seog JS Choe Wonchae W Kang Insug I Ha Joohun J Kim Sung Soo SS
Oncotarget 20151001 31
Colorectal cancer (CRC) is the third leading cause of global cancer mortality. Recent studies have proposed several gene signatures to predict CRC prognosis, but none of those have proven reliable for predicting prognosis in clinical practice yet due to poor reproducibility and molecular heterogeneity. Here, we have established a prognostic signature of 113 probe sets (CRC-113) that include potential biomarkers and reflect the biological and clinical characteristics. Robustness and accuracy were ...[more]
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