Dataset Information

Impact of opioid substitution therapy for Scotland's prisoners on drug-related deaths soon after prisoner release.

ABSTRACT:

Aim

To assess whether the introduction of a prison-based opioid substitution therapy (OST) policy was associated with a reduction in drug-related deaths (DRD) within 14?days after prison release.

Design

Linkage of Scotland's prisoner database with death registrations to compare periods before (1996-2002) and after (2003-07) prison-based OST was introduced.

Setting

All Scottish prisons.

Participants

People released from prison between 1?January 1996 and 8?October 2007 following an imprisonment of at least 14?days and at least 14?weeks after the preceding qualifying release.

Measurements

Risk of DRD in the 12?weeks following release; percentage of these DRDs which occurred during the first 14?days.

Findings

Before prison-based OST (1996-2002), 305 DRDs occurred in the 12?weeks after 80?200 qualifying releases, 3.8 per 1000 releases [95% confidence interval (CI)?=?3.4-4.2]; of these, 175 (57%) occurred in the first 14?days. After the introduction of prison-based OST (2003-07), 154 DRDs occurred in the 12?weeks after 70?317 qualifying releases, a significantly reduced rate of 2.2 per 1000 releases (95% CI?=?1.8-2.5). However, there was no change in the proportion which occurred in the first 14?days, either for all DRDs (87: 56%) or for opioid-related DRDs.

Conclusions

Following the introduction of a prison-based opioid substitution therapy (OST) policy in Scotland, the rate of drug-related deaths in the 12?weeks following release fell by two-fifths. However, the proportion of deaths that occurred in the first 14?days did not change appreciably, suggesting that in-prison OST does not reduce early deaths after release.

SUBMITTER: Bird SM

PROVIDER: S-EPMC4744745 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Impact of opioid substitution therapy for Scotland's prisoners on drug-related deaths soon after prisoner release.

Bird Sheila M SM Fischbacher Colin M CM Graham Lesley L Fraser Andrew A

Addiction (Abingdon, England) 20150608 10

<h4>Aim</h4>To assess whether the introduction of a prison-based opioid substitution therapy (OST) policy was associated with a reduction in drug-related deaths (DRD) within 14 days after prison release.<h4>Design</h4>Linkage of Scotland's prisoner database with death registrations to compare periods before (1996-2002) and after (2003-07) prison-based OST was introduced.<h4>Setting</h4>All Scottish prisons.<h4>Participants</h4>People released from prison between 1 January 1996 and 8 October 2007 ...[more]

PMID: 25940815

Similar Datasets

Project description:BackgroundOpioid-related mortality is high and increasing in the Western world, and interventions aimed at reducing opioid-related deaths represent an important area of study. In Skåne County, Sweden, a patient choice reform resulted in increased access to opioid substitution treatment (OST). In addition, a gradual shift towards less restrictive terms for exclusion from OST has been implemented. The aim of this study was to assess the impact of these policy changes on opioid-related deaths.MethodsDetailed data on opioid-related deaths in Skåne during the 2 years prior to and following the policy change were obtained from forensic records and from health care services. Data on overdose deaths for Skåne and the rest of Sweden were obtained using publicly available national register data. Time periods were used as the predictor for opioid-related deaths in the forensic data. The national level data were used in a natural experiment design in which rates of overdose deaths were compared between Skåne and the rest of Sweden before and after the intervention.ResultsThere was no significant difference in the number of deaths in Skåne between the data collection periods (RR: 1.18 95% CI:0.89-1.57, p= 0.251). The proportion of deaths among patients enrolled in OST increased between the two periods (2.61, 1.12-6.10, p= 0.026). There was no change in deaths related to methadone or buprenorphine in relation to deaths due to the other opioids included in the study (0.92, 0.51-1.63, p= 0.764). An analysis of national mortality data showed an annual relative decrease in unintentional drug deaths in Skåne compared to the rest of Sweden following the onset of the reform (0.90, 0.84-0,97, p= 0.004).ConclusionsOpioid-related deaths, as assessed using forensic data, has not changed significantly in Skåne following a change to lower-threshold OST. By contrast, national level data indicate that the policy change has been associated with decreased overdose deaths. The discrepancy between these results highlights the need for more research to elucidate this issue. The result that more patients die during ongoing OST following an increase in access to treatment underlines the need for further preventive interventions within the OST treatment setting.

Dataset Information

Impact of opioid substitution therapy for Scotland's prisoners on drug-related deaths soon after prisoner release.

Aim

Design

Setting

Participants

Measurements

Findings

Conclusions

Publications

Impact of opioid substitution therapy for Scotland's prisoners on drug-related deaths soon after prisoner release.

Similar Datasets

OmicsDI is part of the ELIXIR infrastructure

Tweets