Ontology highlight
ABSTRACT:
SUBMITTER: Clark ES
PROVIDER: S-EPMC4747030 | biostudies-literature | 2015 Nov-Dec
REPOSITORIES: biostudies-literature
Clark Elizabeth S ES Pepper Victoria K VK Best Cameron A CA Onwuka Ekene A EA Yi Tai T Tara Shuhei S Cianciolo Rachel R Baker Peter P Shinoka Toshiharu T Breuer Christopher K CK
Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 20150808 6
<h4>Background</h4>Endocardial fibroelastosis (EFE) is a pathologic condition of abnormal deposition of collagen and elastin within the endocardium of the heart. It is seen in conjunction with a variety of diseases including hypoplastic left heart syndrome and viral endocarditis. While an experimental model using heterotopic heart transplant in rats has been described, we sought to fully describe a mouse model that can be used to further elucidate the potential mechanisms of and treatments for E ...[more]