Ontology highlight
ABSTRACT:
SUBMITTER: Martinez-Fernandez M
PROVIDER: S-EPMC4747223 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Martínez-Fernández Mónica M Dueñas Marta M Feber Andrew A Segovia Cristina C García-Escudero Ramón R Rubio Carolina C López-Calderón Fernando F FF Díaz-García Claudio C Villacampa Felipe F Duarte José J Gómez-Rodriguez María J MJ Castellano Daniel D Rodriguez-Peralto José L JL de la Rosa Federico F Beck Stephan S Paramio Jesús M JM
Oncotarget 20151201 39
Bladder cancer (BC) is a highly prevalent disease, ranking fifth in the most common cancers worldwide. Various miRNAs have recently emerged as potential prognostic biomarkers in cancer. The miR-200 family, which repressed the epithelial-to-mesenchymal transition (EMT), is repressed in multiple advanced cancers. However, its expression and function in BC is still poorly understood. Here we show that miR-200 family displays increased expression, probably due to the activation of specific oncogenic ...[more]