Ontology highlight
ABSTRACT:
SUBMITTER: Guo XF
PROVIDER: S-EPMC4747679 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Guo Xiao-Feng XF Arceo Jennifer J Huge Bonnie Jaskowski BJ Ludwig Katelyn R KR Dovichi Norman J NJ
The Analyst 20160201 4
Low molecular weight thiol compounds play crucial roles in many physiological processes. Most methods for determination of thiol compounds are population-averaged; few methods for quantification of thiol compounds in single cells have been reported. We report an ultrasensitive method for determination of thiol compounds in single cells by use of 1,3,5,7-tetramethyl-8-phenyl-(2-maleimide)-difluoroboradiaza-s-indacene (TMPAB-o-M), a fluorogenic probe with useful spectral properties, coupled with c ...[more]