Ontology highlight
ABSTRACT:
SUBMITTER: Salogiannis J
PROVIDER: S-EPMC4748578 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Salogiannis John J Egan Martin J MJ Reck-Peterson Samara L SL
The Journal of cell biology 20160125 3
Eukaryotic cells use microtubule-based intracellular transport for the delivery of many subcellular cargos, including organelles. The canonical view of organelle transport is that organelles directly recruit molecular motors via cargo-specific adaptors. In contrast with this view, we show here that peroxisomes move by hitchhiking on early endosomes, an organelle that directly recruits the transport machinery. Using the filamentous fungus Aspergillus nidulans we found that hitchhiking is mediated ...[more]