Ontology highlight
ABSTRACT:
SUBMITTER: Sun J
PROVIDER: S-EPMC4750994 | biostudies-literature | 2016
REPOSITORIES: biostudies-literature
Sun Jiarui J Zhang Xinchen X Cao Yinan Y Zhao Qiling Q Bao Endong E Lv Yingjun Y
PloS one 20160211 2
Although the toxicity of melamine to the kidneys and testes is well known, few studies have investigated the effects of melamine on female reproductive organs. Therefore, this study explores the effects of oral administration melamine or melamine and cyanuric acid for 28 days on the ovaries of female rats. Rats that were exposed to the mixture exhibited reduced ovarian and uterine weights, a shorter estrous cycle, and reduced serum estrogen and progesterone levels compared to rats that were expo ...[more]