Endoscopic sleeve gastroplasty with 1-year follow-up: factors predictive of success.

ABSTRACT: BACKGROUND AND STUDY AIMS:Bariatric endoscopy has emerged as an aid in the nonsurgical treatment of obesity. The objective of this study is to critically provide the results and follow-up of endoscopic sleeve gastroplasty 1 year after the procedure. PATIENTS AND METHODS:Prospective single-center follow-up study of 25 patients (5 men, 20 women) who underwent flexible endoscopic suturing for endoluminal gastric volume reduction. A multidisciplinary team provided post-procedure care. Patient outcomes were recorded at 1 year after the procedure. Linear regression analysis was done to evaluate the variables associated with best results at 1 year of follow-up. RESULTS:Mean body mass index (BMI) was 38.5?±?4.6?kg/m(2) (range 30?-?47) and mean age 44.5?±?8.2 years (range 29?-?60). At 1 year, 22 patients continued with the follow-up (2 dropped out at 6 months and 1?at 3 months). There were no major intra-procedural, early, or delayed adverse events. Mean BMI loss was 7.3?±?4.2?kg/m(2), and mean percentage of total body weight loss was 18.7?±?10.7?at 1 year. In the linear regression analysis, adjusted by initial BMI, variables associated with %TBWL involved the frequency of nutritional (??=?0.563, P?=?0.014) and psychological contacts (??=?0.727, P?=?0.025). The number of nutritional and psychological contacts were predictive of good weight loss results. CONCLUSIONS:Endoscopic sleeve gastroplasty is a feasible, reproducible, and effective procedure to treat obesity. Nutritional and psychological interaction are predictive of success.

SUBMITTER: Lopez-Nava G 

PROVIDER: S-EPMC4751018 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature