Randomized trial of telephone outreach to improve medication adherence and metabolic control in adults with diabetes.

ABSTRACT:

Objective

Medication nonadherence is a major obstacle to better control of glucose, blood pressure (BP), and LDL cholesterol in adults with diabetes. Inexpensive effective strategies to increase medication adherence are needed.

Research design and methods

In a pragmatic randomized trial, we randomly assigned 2,378 adults with diabetes mellitus who had recently been prescribed a new class of medication for treating elevated levels of glycated hemoglobin (A1C) ≥8% (64 mmol/mol), BP ≥140/90 mmHg, or LDL cholesterol ≥100 mg/dL, to receive 1) one scripted telephone call from a diabetes educator or clinical pharmacist to identify and address nonadherence to the new medication or 2) usual care. Hierarchical linear and logistic regression models were used to assess the impact on 1)

SUBMITTER: O'Connor PJ 

PROVIDER: S-EPMC4751474 | biostudies-literature | 2014 Dec

REPOSITORIES: biostudies-literature