Ontology highlight
ABSTRACT:
SUBMITTER: Park M
PROVIDER: S-EPMC4751484 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Park Miree M Lee Youngeun Y Jang Hoon H Lee Ok-Hee OH Park Sung-Won SW Kim Jae-Hwan JH Hong Kwonho K Song Hyuk H Park Se-Pill SP Park Yun-Yong YY Ko Jung Jae JJ Choi Youngsok Y
Scientific reports 20160212
Spermatogenesis- and oogenesis-specific helix-loop-helix transcription factor 2 (SOHLH2) is exclusively expressed in germ cells of the gonads. Previous studies show that SOHLH2 is critical for spermatogenesis in mouse. However, the regulatory mechanism of SOHLH2 during early spermatogenesis is poorly understood. In the present study, we analyzed the gene expression profile of the Sohlh2-deficient testis and examined the role of SOHLH2 during spermatogenesis. We found 513 genes increased in abund ...[more]