Preparation of Au-polydopamine functionalized carbon encapsulated Fe₃O₄ magnetic nanocomposites and their application for ultrasensitive detection of carcino-embryonic antigen.

ABSTRACT: A novel carbon encapsulated Fe3O4 nanoparticles embedded in two-dimensional (2D) porous graphitic carbon nanocomposites (Fe3O4@C@PGC nanocomposites) were synthesized by situ synthesis strategy, which provided a sensor platform owing to a large aspect ratio and porous structure. Polydopamine (PDA) were modified on the surface of Fe3O4@C@PGC nanocomposites through self-polymerization of dopamine, acting as both the reductant and template for one-step synthesis of gold nanoparticles. The prepared Au/PDA/Fe3O4@C@PGC nanocomposites show ferromagnetic features, extremely excellent electron transfer, large specific surface area and excellent dispersing property. These are conducive to the electrochemical signal output and the immobilization of antibody. In this work, a highly label-free sensitive

SUBMITTER: Ji L 

PROVIDER: S-EPMC4751493 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature