Ontology highlight
ABSTRACT:
SUBMITTER: Deng Y
PROVIDER: S-EPMC4751511 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Deng Yi Y Chang Changgee C Ido Moges Seyoum MS Long Qi Q
Scientific reports 20160212
Multiple imputation (MI) has been widely used for handling missing data in biomedical research. In the presence of high-dimensional data, regularized regression has been used as a natural strategy for building imputation models, but limited research has been conducted for handling general missing data patterns where multiple variables have missing values. Using the idea of multiple imputation by chained equations (MICE), we investigate two approaches of using regularized regression to impute mis ...[more]