Application of imaging mass spectrometry for the molecular diagnosis of human breast tumors.
Ontology highlight
ABSTRACT:
SUBMITTER: Mao X
PROVIDER: S-EPMC4751527 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Publications
Application of imaging mass spectrometry for the molecular diagnosis of human breast tumors.
Mao Xinxin X He Jiuming J Li Tiegang T Lu Zhaohui Z Sun Jian J Meng Yunxiao Y Abliz Zeper Z Chen Jie J
Scientific reports 20160212
Distinguishing breast invasive ductal carcinoma (IDC) and breast ductal carcinoma in situ (DCIS) is a key step in breast surgery, especially to determine whether DCIS is associated with tumor cell micro-invasion. However, there is currently no reliable method to obtain molecular information for breast tumor analysis during surgery. Here, we present a novel air flow-assisted ionization (AFAI) mass spectrometry imaging method that can be used in ambient environments to differentiate breast cancer ...[more]
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