Clinical Research and the Training of Host Country Investigators: Essential Health Priorities for Disease-Endemic Regions.

ABSTRACT: The health-care needs and resources of disease-endemic regions such as west Africa have been a major focus during the recent Ebola outbreak. On the basis of that experience, we call attention to two priorities that have unfortunately been ignored thus far: 1) the development of clinical research facilities and 2) the training of host country investigators to ensure that the facilities and expertise necessary to evaluate candidate interventions are available on-site in endemic regions when and where they are needed. In their absence, as illustrated by the recent uncertainty about the use of antivirals and other interventions for Ebola virus disease, the only treatment available may be supportive care, case fatality rates may be unacceptably high and there may be long delays between the time

SUBMITTER: Koita OA 

PROVIDER: S-EPMC4751934 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature