Ontology highlight
ABSTRACT:
SUBMITTER: Cifuentes M
PROVIDER: S-EPMC4752240 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Cifuentes Marta M Jolivet Sylvie S Cromer Laurence L Harashima Hirofumi H Bulankova Petra P Renne Charlotte C Crismani Wayne W Nomura Yuko Y Nakagami Hirofumi H Sugimoto Keiko K Schnittger Arp A Riha Karel K Mercier Raphael R
PLoS genetics 20160212 2
Cell cycle control must be modified at meiosis to allow two divisions to follow a single round of DNA replication, resulting in ploidy reduction. The mechanisms that ensure meiosis termination at the end of the second and not at the end of first division are poorly understood. We show here that Arabidopsis thaliana TDM1, which has been previously shown to be essential for meiotic termination, interacts directly with the Anaphase-Promoting Complex. Further, mutations in TDM1 in a conserved putati ...[more]