Neurocognitive and Patient-Reported Outcomes in Adult Survivors of Childhood Osteosarcoma.

ABSTRACT:

Importance

This study provides the first objective data documenting neurocognitive impairment in long-term survivors of childhood osteosarcoma.

Objective

To examine neurocognitive, neurobehavioral, emotional, and quality-of-life outcomes in long-term survivors of childhood osteosarcoma.

Design, setting, and participants

Cross-sectional cohort study at an academic research hospital, with prospective treatment and chronic health predictors. Outcome data were collected from June 2008 to August 2014. Data analysis was completed in April 2015. Survivors of osteosarcoma recruited from the St Jude Lifetime Cohort Study were compared with community controls.

Main outcomes and measures

Neurocognitive function, neurobehavioral symptoms, emotional distress, and quality of

SUBMITTER: Edelmann MN 

PROVIDER: S-EPMC4752424 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature