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Diabetes mellitus and venous thromboembolism: A systematic review and meta-analysis.


ABSTRACT:

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Diabetes mellitus (DM) may be a risk factor for venous thromboembolism (VTE) but results are inconsistent.

Aim

We conducted a systematic review and meta-analysis of epidemiologic studies to quantify the association between DM and VTE.

Methods and results

We included studies identified in PubMed, Web of Science, and CINAHL through 07/31/2014. We identified 19 studies that met our selection criteria. We pooled RRs using a random-effects model: the pooled RR for the association of DM with VTE was 1.10 (95% CI: 0.94-1.29). Between-study heterogeneity was explored with a forest plot, funnel plot, meta-regression, and a stratified analysis. Between-study heterogeneity was observed and not explained by study design, method of DM assessment, or degree of adjustment

SUBMITTER: Bell EJ 

PROVIDER: S-EPMC4752919 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature