Ontology highlight
ABSTRACT:
SUBMITTER: Ng JH
PROVIDER: S-EPMC4753418 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Ng Justin H J JH Tachedjian Mary M Deakin Janine J Wynne James W JW Cui Jie J Haring Volker V Broz Ivano I Chen Honglei H Belov Katherine K Wang Lin-Fa LF Baker Michelle L ML
Scientific reports 20160215
Bats are natural hosts to numerous viruses and have ancient origins, having diverged from other eutherian mammals early in evolution. These characteristics place them in an important position to provide insights into the evolution of the mammalian immune system and antiviral immunity. We describe the first detailed partial map of a bat (Pteropus alecto) MHC-I region with comparative analysis of the MHC-I region and genes. The bat MHC-I region is highly condensed, yet relatively conserved in orga ...[more]