Ontology highlight
ABSTRACT:
SUBMITTER: Chen IC
PROVIDER: S-EPMC4753425 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Chen I-Chun IC Chang Yuan-Ching YC Lu Yen-Shen YS Chung Kuei-Pin KP Huang Chiun-Sheng CS Lu Tzu-Pin TP Kuo Wen-Hung WH Wang Ming-Yang MY Kuo Kuan-Ting KT Wu Pei-Fang PF Hsueh Tsu-Hsin TH Shen Chen-Yang CY Lin Ching-Hung CH Cheng Ann-Lii AL
Scientific reports 20160215
Liver kinase B1 (LKB1) is a tumor suppressor, and its loss might lead to activation of the mammalian target of rapamycin (mTOR) and tumorigenesis. This study aimed to determine the clinical relevance of LKB1 gene and protein expression in breast cancer patients. LKB1 protein expression was evaluated using immunohistochemistry in tumors from early breast cancer patients in two Taiwanese medical centers. Data on LKB1 gene expression were obtained from the Molecular Taxonomy of Breast Cancer Intern ...[more]