Photocleavable Hydrogels for Light-Triggered siRNA Release.

ABSTRACT: A photocleavable hydrogel system for on-demand delivery of genetic material is reported. The release of short interfering RNAs can be triggered by the application of UV light without any loss in bioactivity. This approach provides a promising external stimulus-based nucleic acid delivery platform for applications in disease therapeutics and tissue regeneration.

SUBMITTER: Huynh CT 

PROVIDER: S-EPMC4755586 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature