Ontology highlight
ABSTRACT:
SUBMITTER: Kenkre VP
PROVIDER: S-EPMC4755793 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Kenkre Vaishalee P VP Hong Fangxin F Cerhan James R JR Lewis Marcia M Sullivan Leslie L Williams Michael E ME Gascoyne Randy D RD Horning Sandra J SJ Kahl Brad S BS
Clinical cancer research : an official journal of the American Association for Cancer Research 20151028 4
<h4>Purpose</h4>Preclinical studies suggest that SNPs in the Fc gamma receptor (FCGR) genes influence response to rituximab, but the clinical relevance of this is uncertain.<h4>Experimental design</h4>We prospectively obtained specimens for genotyping in the rituximab extended schedule or re-treatment trial (RESORT) study, in which 408 previously untreated, low tumor burden follicular lymphoma (FL) patients were treated with single agent rituximab. Patients received rituximab in 4 weekly doses a ...[more]