Red Blood Cell Fatty Acids and Incident Diabetes Mellitus in the Women's Health Initiative Memory Study.

ABSTRACT:

Context

The relations between dietary and/or circulating levels of fatty acids and the development of type 2 diabetes is unclear. Protective associations with the marine omega-3 fatty acids and linoleic acid, and with a marker of fatty acid desaturase activity delta-5 desaturase (D5D ratio) have been reported, as have adverse relations with saturated fatty acids and D6D ratio.

Objective

To determine the associations between red blood cell (RBC) fatty acid distributions and incident type 2 diabetes.

Design

Prospective observational cohort study nested in the Women's Health Initiative Memory Study.

Setting

General population.

Subjects

Postmenopausal women.

Main outcome measures

Self-reported incident type 2 diabetes.

Results

There were 703 ne

SUBMITTER: Harris WS 

PROVIDER: S-EPMC4755935 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature