Ontology highlight
ABSTRACT:
SUBMITTER: Miller VM
PROVIDER: S-EPMC4757027 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Miller Virginia M VM Jenkins Gregory D GD Biernacka Joanna M JM Heit John A JA Huggins Gordon S GS Hodis Howard N HN Budoff Matthew J MJ Lobo Rogerio A RA Taylor Hugh S HS Manson JoAnn E JE Black Dennis M DM Naftolin Frederick F Harman S Mitchell SM de Andrade Mariza M
Physiological genomics 20151027 1
Prior to the initiation of menopausal hormone treatment (MHT), genetic variations in the innate immunity pathway were found to be associated with carotid artery intima-medial thickness (CIMT) and coronary arterial calcification (CAC) in women (n = 606) enrolled in the Kronos Early Estrogen Prevention Study (KEEPS). Whether MHT might affect these associations is unknown. The association of treatment outcomes with variation in the same 764 candidate genes was evaluated in the same KEEPS participan ...[more]