Ontology highlight
ABSTRACT:
SUBMITTER: Lobkovsky AE
PROVIDER: S-EPMC4758245 | biostudies-literature | 2015 Dec
REPOSITORIES: biostudies-literature
Lobkovsky Alexander E AE Wolf Yuri I YI Koonin Eugene V EV
Genome biology and evolution 20151210 1
Evolution and maintenance of genetic recombination and its relation to the mutational process is a long-standing, fundamental problem in evolutionary biology that is linked to the general problem of evolution of evolvability. We explored a stochastic model of the evolution of recombination using additive fitness and infinite allele assumptions but no assumptions on the sign or magnitude of the epistasis and the distribution of mutation effects. In this model, fluctuating negative epistasis and p ...[more]