Inositol transporters AtINT2 and AtINT4 regulate arsenic accumulation in Arabidopsis seeds.

ABSTRACT: Arsenic contamination of groundwater and soils threatens the health of tens of millions of people worldwide. Understanding the way in which arsenic is taken up by crops such as rice, which serve as a significant source of arsenic in the human diet, is therefore important. Membrane transport proteins that catalyse arsenic uptake by roots, and translocation through the xylem to shoots, have been characterized in a number of plants, including rice. The transporters responsible for loading arsenic from the xylem into the phloem and on into the seeds, however, are yet to be identified. Here, we show that transporters responsible for inositol uptake in the phloem in Arabidopsis also transport arsenic. Transformation of Saccharomyces cerevisiae with AtINT2 or AtINT4 led to increased arsenic accum

SUBMITTER: Duan GL 

PROVIDER: S-EPMC4758254 | biostudies-literature | 2016 Jan

REPOSITORIES: biostudies-literature