Ontology highlight
ABSTRACT:
SUBMITTER: Kolli MB
PROVIDER: S-EPMC4758344 | biostudies-literature | 2014 Dec
REPOSITORIES: biostudies-literature
Kolli Madhukar B MB Manne Nandini D P K NDPK Para Radhakrishna R Nalabotu Siva K SK Nandyala Geeta G Shokuhfar Tolou T He Kun K Hamlekhan Azhang A Ma Jane Y JY Wehner Paulette S PS Dornon Lucy L Arvapalli Ravikumar R Rice Kevin M KM Blough Eric R ER
Biomaterials 20140915 37
Cerium oxide (CeO2) nanoparticles have been posited to exhibit potent anti-oxidant activity which may allow for the use of these materials in biomedical applications. Herein, we investigate whether CeO2 nanoparticle administration can diminish right ventricular (RV) hypertrophy following four weeks of monocrotaline (MCT)-induced pulmonary arterial hypertension (PAH). Male Sprague Dawley rats were randomly divided into three groups: control, MCT only (60 mg/kg), or MCT + CeO2 nanoparticle treatme ...[more]