Quantitative analysis of urea in human urine and serum by 1H nuclear magnetic resonance.
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ABSTRACT:
SUBMITTER: Liu L
PROVIDER: S-EPMC4758351 | biostudies-literature | 2012 Feb
REPOSITORIES: biostudies-literature
Publications
Quantitative analysis of urea in human urine and serum by 1H nuclear magnetic resonance.
Liu Lingyan L Mo Huaping H Wei Siwei S Raftery Daniel D
The Analyst 20111216 3
A convenient and fast method for quantifying urea in biofluids is demonstrated using NMR analysis and the solvent water signal as a concentration reference. The urea concentration can be accurately determined with errors less than 3% between 1 mM and 50 mM, and less than 2% above 50 mM in urine and serum. The method is promising for various applications with advantages of simplicity, high accuracy, and fast non-destructive detection. With an ability to measure other metabolites simultaneously, t ...[more]
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