Ontology highlight
ABSTRACT:
SUBMITTER: Abraham HM
PROVIDER: S-EPMC4758547 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
Abraham Hazel Mae A HM Wolfson Leslie L Moscufo Nicola N Guttmann Charles R G CR Kaplan Richard F RF White William B WB
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20160101 1
Several potential vascular risk factors exist for the development and accumulation of subcortical white matter disease in older people. We have reported that in older people followed for up to 4 years white matter hyperintensity (WMH) lesions on magnetic resonance imaging nearly doubled in volume and were associated with alterations in mobility and cognitive function. Herein we review the genetic, metabolic, and vascular risk factors that have been evaluated in association with the development a ...[more]