Ontology highlight
ABSTRACT:
SUBMITTER: Gouty-Colomer LA
PROVIDER: S-EPMC4759206 | biostudies-literature | 2016 Mar
REPOSITORIES: biostudies-literature
Molecular psychiatry 20150324 3
Memories are encoded within sparsely distributed neuronal ensembles. However, the defining cellular properties of neurons within a memory trace remain incompletely understood. Using a fluorescence-based Arc reporter, we were able to visually identify the distinct subset of lateral amygdala (LA) neurons activated during auditory fear conditioning. We found that Arc-expressing neurons have enhanced intrinsic excitability and are preferentially recruited into newly encoded memory traces. Furthermor ...[more]