Ontology highlight
ABSTRACT:
SUBMITTER: Mirshafian R
PROVIDER: S-EPMC4760353 | biostudies-literature | 2016 Feb
REPOSITORIES: biostudies-literature
Mirshafian Razieh R Wei Wei W Israelachvili Jacob N JN Waite J Herbert JH
Biochemistry 20160122 5
Dopa (l-3,4-dihydroxyphenylalanine) is a key chemical signature of mussel adhesive proteins, but its susceptibility to oxidation has limited mechanistic investigations as well as practical translation to wet adhesion technology. To investigate peptidyl-Dopa oxidation, the highly diverse chemical environment of Dopa in mussel adhesive proteins was simplified to a peptidyl-Dopa analogue, N-acetyl-Dopa ethyl ester. On the basis of cyclic voltammetry and UV-vis spectroscopy, the Dopa oxidation produ ...[more]