Monoalkylglycerol ether lipids promote adipogenesis.
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ABSTRACT:
SUBMITTER: Homan EA
PROVIDER: S-EPMC4761264 | biostudies-literature | 2011 Apr
REPOSITORIES: biostudies-literature
Publications
Monoalkylglycerol ether lipids promote adipogenesis.
Homan Edwin A EA Kim Yun-Gon YG Cardia James P JP Saghatelian Alan A
Journal of the American Chemical Society 20110323 14
The molecular mechanisms that lead to the generation of adipose tissue (adipogenesis) are of basic and biomedical interest. Cellular models of adipogenesis have proven extremely valuable in defining biomolecules-primarily genes and proteins-that regulate adipogenesis. Here, the analysis of differentiating adipocytes using an untargeted metabolomics approach led to the discovery of the monoalkylglycerol ethers as a natural class of adipocyte differentiation factors. ...[more]
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