Morphogenetic implications of peristaltic fluid-tissue dynamics in the embryonic lung.
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ABSTRACT:
SUBMITTER: Bokka KK
PROVIDER: S-EPMC4762031 | biostudies-literature | 2015 Oct
REPOSITORIES: biostudies-literature
Publications
Morphogenetic implications of peristaltic fluid-tissue dynamics in the embryonic lung.
Bokka Kishore K KK Jesudason Edwin C EC Warburton David D Lubkin Sharon R SR
Journal of theoretical biology 20150710
Peristalsis begins in the lung as soon as the smooth muscle forms, and persists until birth. Since the prenatal lung is liquid-filled, smooth muscle action can deform tissues and transport fluid far from the immediately adjacent tissues. Stretching of embryonic tissues and sensation of internal fluid flows have been shown to have potent morphogenetic effects. We hypothesize that these effects are at work in lung morphogenesis. To place that hypothesis in a quantitative framework, we analyze a mo ...[more]
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