Vascular factors in suspected normal pressure hydrocephalus: A population-based study.

ABSTRACT:

Objective

We examined clinical and imaging findings of suspected idiopathic normal pressure hydrocephalus (iNPH) in relation to vascular risk factors and white matter lesions (WMLs), using a nested case-control design in a representative, population-based sample.

Methods

From a population-based sample, 1,235 persons aged 70 years or older were examined with CT of the brain between 1986 and 2000. We identified 55 persons with hydrocephalic ventricular enlargement, i.e., radiologic findings consistent with iNPH. Among these, 26 had clinical signs that fulfilled international guideline criteria for probable iNPH. These cases were labeled suspected iNPH. Each case was matched to 5 controls from the same sample, based on age, sex, and study cohort. Data on risk factors were obtai

SUBMITTER: Jaraj D 

PROVIDER: S-EPMC4762415 | biostudies-literature | 2016 Feb

REPOSITORIES: biostudies-literature