Dataset Information

Long Term Outcomes of a Geriatric Liaison Intervention in Frail Elderly Cancer Patients.

ABSTRACT:

Background

The aim of this study was to evaluate the long term effects after discharge of a hospital-based geriatric liaison intervention to prevent postoperative delirium in frail elderly cancer patients treated with an elective surgical procedure for a solid tumour. In addition, the effect of a postoperative delirium on long term outcomes was examined.

Methods

A three month follow-up was performed in participants of the Liaison Intervention in Frail Elderly study, a multicentre, prospective, randomized, controlled trial. Patients were randomized to standard treatment or a geriatric liaison intervention. The intervention consisted of a preoperative geriatric consultation, an individual treatment plan targeted at risk factors for delirium and daily visits by a geriatric nurse during the hospital stay. The long term outcomes included: mortality, rehospitalisation, Activities of Daily Living (ADL) functioning, return to the independent pre-operative living situation, use of supportive care, cognitive functioning and health related quality of life.

Results

Data of 260 patients (intervention n = 127, Control n = 133) were analysed. There were no differences between the intervention group and usual-care group for any of the outcomes three months after discharge. The presence of postoperative delirium was associated with: an increased risk of decline in ADL functioning (OR: 2.65, 95% CI: 1.02-6.88), an increased use of supportive assistance (OR: 2.45, 95% CI: 1.02-5.87) and a decreased chance to return to the independent preoperative living situation (OR: 0.18, 95% CI: 0.07-0.49).

Conclusions

A hospital-based geriatric liaison intervention for the prevention of postoperative delirium in frail elderly cancer patients undergoing elective surgery for a solid tumour did not improve outcomes 3 months after discharge from hospital. The negative effect of a postoperative delirium on late outcome was confirmed.

Trial registration

Nederlands Trial Register, Trial ID NTR 823.

SUBMITTER: Hempenius L

PROVIDER: S-EPMC4762573 | biostudies-literature | 2016

REPOSITORIES: biostudies-literature

ACCESS DATA

Publications

Long Term Outcomes of a Geriatric Liaison Intervention in Frail Elderly Cancer Patients.

Hempenius Liesbeth L Slaets Joris P J JP van Asselt Dieneke D de Bock Truuske H TH Wiggers Theo T van Leeuwen Barbara L BL

PloS one 20160222 2

<h4>Background</h4>The aim of this study was to evaluate the long term effects after discharge of a hospital-based geriatric liaison intervention to prevent postoperative delirium in frail elderly cancer patients treated with an elective surgical procedure for a solid tumour. In addition, the effect of a postoperative delirium on long term outcomes was examined.<h4>Methods</h4>A three month follow-up was performed in participants of the Liaison Intervention in Frail Elderly study, a multicentre, ...[more]

PMID: 26901417

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Dataset Information

Long Term Outcomes of a Geriatric Liaison Intervention in Frail Elderly Cancer Patients.

Background

Methods

Results

Conclusions

Trial registration

Publications

Long Term Outcomes of a Geriatric Liaison Intervention in Frail Elderly Cancer Patients.

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