Ontology highlight
ABSTRACT:
SUBMITTER: Yamout A
PROVIDER: S-EPMC4764251 | biostudies-literature | 2005 Sep-Oct
REPOSITORIES: biostudies-literature
Developmental neuroscience 20050901 5
We investigated which neurotrophic factors may contribute to the divergence of two peripheral nerves emanating from the geniculate ganglion. We compared receptor mRNA profiles of the neurons that supply the nerves, and also the growth of their neurites in response to neurotrophic factors in culture. Three mRNAs, Gfra2, TrkA, and TrkC, were differentially expressed. Only one ligand, Neurturin, promoted substantially different nerve regrowth from the nerves, and therefore may contribute to nerve d ...[more]